Usefulness of the trabecular bone score for assessing the risk of osteoporotic fracture

Autor: L. Redondo, Pilar Peris, E. Puigoriol, José Ruiz Rodríguez, E. Kanterewicz
Rok vydání: 2018
Předmět:
Zdroj: Revista Clínica Española (English Edition). 218:121-127
ISSN: 2254-8874
DOI: 10.1016/j.rceng.2017.12.002
Popis: Introduction and objectives The trabecular bone score (TBS) is an imaging technique that assesses the condition of the trabecular microarchitecture. Preliminary results suggest that TBS, along with the bone mineral density assessment, could improve the calculation of the osteoporotic fracture risk. The aim of this study was to analyze TBS values and their relationship with the clinical characteristics, bone mineral density and history of fractures of a cohort of posmenopausal women. Materials and methods We analyzed 2257 posmenopausal women from the FRODOS cohort, which was created to determine the risk factors for osteoporotic fracture through a clinical survey and bone densitometry with vertebral morphometry. TBS was applied to the densitometry images. TBS values ≤1230 were considered indicative of degraded microarchitecture. We performed a simple and multiple linear regression to determine the factors associated with this index. Results The mean TBS value in L1–L4 was 1.203 ± 0.121. Some 55.3% of the women showed values indicating degraded microarchitecture. In the multiple linear regression analysis, the factors associated with low TBS values were age, weight, height, spinal T-score, glucocorticoid treatment, presence of type 2 diabetes and a history of fractures due to frailty. Conclusions TBS showed microarchitecture degradation values in the participants of the FRODOS cohort and was associated with anthropometric factors, low bone mineral density values, the presence of fractures, a history of type 2 diabetes mellitus and the use of glucocorticoids.
Databáze: OpenAIRE
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