A general synthesis of (2Z)-terpenoic acids
Autor: | Jean-Marie Poirier, Dominique Cahard, Malika Mammeri, Lucette Duhamel |
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Rok vydání: | 2000 |
Předmět: | |
Zdroj: | Tetrahedron Letters. 41:3619-3622 |
ISSN: | 0040-4039 |
DOI: | 10.1016/s0040-4039(00)00457-3 |
Popis: | A three-step synthesis of (2 Z ), (4 E )-polyenic acids 6 is described. Condensation of aldehydes 1 with potassium prenal enolate led to dihydropyranols 3 which were oxidized into dihydropyrones 5 , precursors of (2 Z) , (4 E )-polyenic acids 6 . The procedure was applied to a synthesis of 13- cis -retinoic acids from β-ionylidene acetaldehydes. |
Databáze: | OpenAIRE |
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