AbrB is a regulator of the σWregulon inBacillus subtilis

Autor: Chien Y Lee, John D. Helmann, Mark A Strauch, Qiang Qian
Rok vydání: 2002
Předmět:
Zdroj: FEMS Microbiology Letters. 211:219-223
ISSN: 1574-6968
0378-1097
DOI: 10.1111/j.1574-6968.2002.tb11228.x
Popis: The Bacillus subtilis global regulator AbrB was found to negatively control expression of sigW and genes of the σW regulon. AbrB bound to DNA regions in the autoregulatory sigW promoter and to some, but not all, of the other σW-dependent promoters in B. subtilis. Defects in antibiotic resistance properties caused by spo0A mutations are at least partially correlated with AbrB repression of the σW regulon.
Databáze: OpenAIRE