Clinical analysis of relationship between clot formation in COVID-19 patients and presence of antiphosppholipid
| Autor: | Jullanar Z. Daeweesh, A-S. U. Hassan |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | International journal of health sciences. :11133-11140 |
| ISSN: | 2550-696X 2550-6978 |
| DOI: | 10.53730/ijhs.v6ns5.10934 |
| Popis: | Objective. One of the hallmarks seen in severely sick individuals with coronavirus illness is coagulopathy (COVID-19). Antiphospholipid antibodies (aPLs) play a role in coagulopathy, although their significance in COVID-19 is unknown. The purpose of this study was to identify the prevalence and features of aPLs in COVID-19 patients. Method :80 patients were admite to the hospital .40 of them were positive inRT- PCR test for COVID-19 infection and the other 40 were healthy control. Both groups were tested for the incidence of Anti-phospholipid-Igm Ab. Result: all patient showed higher levels of antiphospholipids antibodies (0.965±2.07) then in control group (0.023±0.0005) with p-value (0.004). Conclusion. Antiphospholipid antibodies were frequently appeared in COVID-19-infected patients. COVID-19 infection might trigger the development of a condition of autoimmunity resamble the antiphospholipid syndrome (APS), forming what called a "COVID-19–induced APS-like syndrome". tasting reports appears medium to high levels of aPLs that would disappear within a few weeks in infected patients. The identification of aPLs would gave appropriate clew for COVID-19 infection. |
| Databáze: | OpenAIRE |
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