Impact of Local Adjuncts to Scaling and Root Planing in Periodontal Disease Therapy: A Systematic Review

Autor: Linda J Lux, Kathleen N. Lohr, Arthur J. Bonito
Rok vydání: 2005
Předmět:
Zdroj: Journal of Periodontology. 76:1227-1236
ISSN: 1943-3670
0022-3492
DOI: 10.1902/jop.2005.76.8.1227
Popis: Background: Chronic periodontitis affects many adults in the United States, some severely enough to threaten tooth loss. Of particular clinical importance is whether scaling and root planing (SRP) accompanied by a local adjunctive therapeutic agent improves outcomes over time compared to SRP alone. The adjunctive therapeutic agents investigated include: tetracycline, minocycline, metronidazole, a group of other antibiotics, chlorhexidine, and a group of antimicrobials. Primary outcomes considered are reductions in probing depth (PD) and gains in clinical attachment level (CAL). Methods: RTI-UNC Evidence-Based Practice Center staff searched MEDLINE (1966 through December 2002) and EMBASE (through February 2002) to identify clinical trials published in English that 1) involved adults with chronic periodontitis but no serious comorbidities; 2) tested one or more chemical antimicrobial agents as an adjunct to SRP alone or with a placebo; 3) had a concurrent control group that received the same SRP as the trea...
Databáze: OpenAIRE
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