Micronized and Heat-Treated Lactobacillus plantarum LM1004 Stimulates Host Immune Responses Via the TLR-2/MAPK/NF-��B Signalling Pathway In Vitro and In Vivo
Autor: | Sarang Cho, Yong Il Park, Ilseon Jung, Sohn Minn, Jisun Lee, Ji Won Choi, Tae Gyu Choi, Chang Won Lee |
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Rok vydání: | 2019 |
Předmět: |
0106 biological sciences
MAPK/ERK pathway Innate immune system biology Chemistry General Medicine biology.organism_classification 01 natural sciences Applied Microbiology and Biotechnology Cell biology Nitric oxide synthase Immune system Mechanism of action 010608 biotechnology Splenocyte medicine biology.protein Secretion medicine.symptom Lactobacillus plantarum Biotechnology |
Zdroj: | Journal of Microbiology and Biotechnology. 29:704-712 |
ISSN: | 1738-8872 1017-7825 |
Popis: | Although nanometric dead Lactobacillus plantarum has emerged as a potentially important modulator of immune responses, its underlying mechanism of action has not been fully understood. This study aimed to identify the detailed biochemical mechanism of immune modulation by micronized and heat-treated L. plantarum LM1004 (MHT-LM1004 |
Databáze: | OpenAIRE |
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