Erythrocyte Sodium-Lithium Countertransport Activity has no Predictive Value for Pregnancy-Induced Hypertension
| Autor: | Tony K.H. Chung, Sally Baldwin, Herman Wong, Swami R. Swaminathan, Mano Arumanayagam, Michael S. Rogers |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
medicine.medical_specialty
Pregnancy Lithium (medication) business.industry Obstetrics and Gynecology Sodium lithium countertransport medicine.disease Essential hypertension Predictive value Endocrinology Internal medicine Internal Medicine Medicine Gestation Pregnancy induced Family history business medicine.drug |
| Zdroj: | Hypertension in Pregnancy. 13:43-50 |
| ISSN: | 1525-6065 1064-1955 |
| DOI: | 10.3109/10641959409084170 |
| Popis: | Objective: Erythrocyte sodium-lithium countertransport (SLC) is elevated in patients with essential hypertension, those with a family history of hypertension, and in normotensive first-degree relatives of hypertensives. Studies on pregnant women have failed to show any difference between normotensive subjects and those with established pregnancy-induced hypertension (PIH). We therefore studied erythrocyte SLC in second and third trimester primigravid women before the onset of clinical signs of PIH to evaluate the predictive value of this test.Method: All the subjects were Chinese primigravid women. Subjects were excluded if they had a family history of hypertension or if there was any hypertensive disease. Erythrocyte SLC was determined from the difference in efflux of lithium from lithium-loaded cells into sodium-containing and sodium-free media.Results: There were no significant differences in the SLC values between subjects who subsequently developed PIH and those who remained normotensive. In both gro... |
| Databáze: | OpenAIRE |
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