Carcinoma of the esophagus in india

Autor: E. J. Borges, J. C. Paymaster, Prafulla B. Desai, V. G. Vohra
Rok vydání: 1969
Předmět:
Zdroj: Cancer. 23:979-989
ISSN: 1097-0142
0008-543X
DOI: 10.1002/1097-0142(196904)23:4<979::aid-cncr2820230436>3.0.co;2-9
Popis: It is as yet an unrecognised fact in geographic pathology that cancer of the esophagus has the highest incidence in India. An analysis of patient material reveals that 51% of cases are too advanced for any treatment at their initial presentation. The authors present their views regarding the management of cancers of the upper third, the middle third and the lower third of the esophagus (excluding the cervical esophagus). Cancers of the middle segment are the most common and the most debated as regards management. Results of radiotherapy and surgery are presented and compared. Those in whom radiotherapy failed have been analyzed critically, and the authors believe that there is a group of patients which could have been salvaged by timely excision of their growths. Thus, radiotherapy and surgery should have a complementary role in the overall management. Preliminary ideas on the value of preoperative irradiation are presented. The ideal method of preoperative irradiation and the ideal surgical approach are still matters of debate and uncertainty. The management of advanced esophageal cancers by chemotherapy is mentioned; and although the overall prognosis of a patient with esophageal cancer still remains poor, earlier diagnosis, the advent of supervoltage therapy, careful surgery and cautious chemotherapy at the optimum time may help to bring the ultimate survival rate of esophageal cancer patients close to that of patients with other malignancies.
Databáze: OpenAIRE
Externí odkaz: