Osteogenic sarcoma of the skull: A rare sequela of pituitary irradiation
Autor: | R. W. Eells, M. Sparagana, S. Stefani, V. Jablokow |
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Rok vydání: | 1972 |
Předmět: | |
Zdroj: | Cancer. 29:1376-1379 |
ISSN: | 1097-0142 0008-543X |
DOI: | 10.1002/1097-0142(197205)29:5<1376::aid-cncr2820290539>3.0.co;2-1 |
Popis: | A patient received multiple courses of kilovoltage radiation therapy and underwent two transfrontal craniotomies, with incomplete removal of a chromophobe adenoma of the pituitary. Twenty-one years after the initial irradiation, he developed osteogenic sarcoma of the frontal bone, a very rare complication. Only two similar cases could be found in the literature. The high total dose, repeated courses of irradiation, and surgically-induced vascular changes in the frontal bone flap may all have contributed to development of the sarcoma. |
Databáze: | OpenAIRE |
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