Osteogenic sarcoma of the skull: A rare sequela of pituitary irradiation

Autor: R. W. Eells, M. Sparagana, S. Stefani, V. Jablokow
Rok vydání: 1972
Předmět:
Zdroj: Cancer. 29:1376-1379
ISSN: 1097-0142
0008-543X
DOI: 10.1002/1097-0142(197205)29:5<1376::aid-cncr2820290539>3.0.co;2-1
Popis: A patient received multiple courses of kilovoltage radiation therapy and underwent two transfrontal craniotomies, with incomplete removal of a chromophobe adenoma of the pituitary. Twenty-one years after the initial irradiation, he developed osteogenic sarcoma of the frontal bone, a very rare complication. Only two similar cases could be found in the literature. The high total dose, repeated courses of irradiation, and surgically-induced vascular changes in the frontal bone flap may all have contributed to development of the sarcoma.
Databáze: OpenAIRE