Cryoglobulinemic vasculitis associated with HCV infection: still a problem?

Autor:	S. Yu. Milovanova, L. V. Lysenko (Kozlovskaya), L. Yu. Milovanova, D. T. Abdurahmanov, M. V. Taranova, A. V. Volkov
Rok vydání:	2022
Předmět:	Nephrology
Zdroj:	Nephrology (Saint-Petersburg). 26:30-39
ISSN:	2541-9439 1561-6274
Popis:	The review presents the main data on the problem of cryoglobulinemic vasculitis associated with HCV infection. The options for the course are considered, and modern diagnostic criteria, the choice of tactics, and the effectiveness of various treatment regimens are presented. The use of modern antiviral drugs makes it possible to achieve the eradication of the virus in 95 % of patients. However, in some patients, clinical and immunologic markers of vasculitis persist despite viral clearance. The article discusses the concept that the persistence of B-cell clones after achieving a sustained virological response may underlie the pathogenesis of HCV-independent CV reactivation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::113e5bd5f087979d51399b4951f06b9b https://doi.org/10.36485/1561-6274-2022-26-3-30-39 Zobrazit plný text záznamu