Overlapping chemical and genetic diversity in Ligularia lamarum and Ligularia subspicata. Isolation of ten new eremophilanes and a new seco-bakkane compound

Autor: Xun Chao, Motoo Tori, Ryo Hanai, Anna Shimizu, Miho Fujiwara, Kanako Mihara, Yuriko Takashima, Xun Gong, Yoshinori Saito, Chiaki Kuroda, Misato Sakaoku, Masato Hattori, Yuko Iwamoto, Yoko Sasaki
Rok vydání: 2011
Předmět:
Zdroj: Tetrahedron. 67:2220-2231
ISSN: 0040-4020
DOI: 10.1016/j.tet.2011.01.082
Popis: Root chemicals and DNA sequences were analyzed for Ligularia lamarum samples collected in Yunnan and Sichuan Provinces of China and the relationship between the plant and Ligularia subspicata, its taxonomically closest species, was examined. Both species produce furanoeremophilanes and eremophilan-8-one derivatives as the major components. Eleven new compounds, including a new seco-bakkane compound, were isolated. The two species were found to harbor overlapping intra-specific diversities with respect to the chemicals and the DNA sequences. (C) 2011 Elsevier Ltd. All rights reserved.
Databáze: OpenAIRE