Systematic Design of Adenosine Analogs as Inhibitors of a Clostridioides difficile-Specific DNA Adenine Methyltransferase Required for Normal Sporulation and Persistence

Autor: Jujun Zhou, John R. Horton, Martina Menna, Francesco Fiorentino, Ren Ren, Dan Yu, Taraneh Hajian, Masoud Vedadi, Giulia Mazzoccanti, Alessia Ciogli, Elmar Weinhold, Michael Hüben, Robert M. Blumenthal, Xing Zhang, Antonello Mai, Dante Rotili, Xiaodong Cheng
Rok vydání: 2022
Předmět:
Zdroj: Journal of Medicinal Chemistry. 66:934-950
ISSN: 1520-4804
0022-2623
DOI: 10.1021/acs.jmedchem.2c01789
Databáze: OpenAIRE