'One-Pot' Technique for Transformation of the Aporphine Alkaloid Boldine into Phenanthrene Seco-Boldine with Subcritical Water

Autor:	Vladimir I. Minkin, S. S. Khizrieva, N. I. Borisenko, S. N. Borisenko, E. V. Maksimenko, A. V. Lekar
Rok vydání:	2020
Předmět:	010304 chemical physics Chemistry Alkaloid One-Step Phenanthrene 010402 general chemistry 01 natural sciences 0104 chemical sciences Catalysis chemistry.chemical_compound Yield (chemistry) 0103 physical sciences Boldine Organic chemistry Aporphine Physical and Theoretical Chemistry
Zdroj:	Russian Journal of Physical Chemistry B. 14:1153-1157
ISSN:	1990-7923 1990-7931
Popis:	A “one-pot” method for the production of phenanthrene seco-boldine from the aporphine alkaloid boldine in subcritical water was developed and studied. The efficiency of the method for the preparation of seco-boldine in subcritical water was studied at temperatures from 100 to 230°C. The “one-pot” technique in subcritical water allows a quantitative yield of seco-boldine in one step without using any catalytic additives. The structure of the product was confirmed by NMR and ESI-MS. The proposed technique does not require the use of expensive and toxic organic solvents. The preparation of seco-boldine by this technique takes 30 min, which makes it possible to develop an inexpensive, environmentally safe procedure for the production of seco-boldine in subcritical water.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::111582153632fb27ef7043869ed3a6e8 https://doi.org/10.1134/s199079312007012x Zobrazit plný text záznamu Full text from SpringerLink