Two-photon probes based on arylsulfonyl azides: Fluorescence detection and imaging of biothiols

Autor:	Alla Sreenivasa Rao, Subhankar Singha, Dokyoung Kim, Taejun Wang, Kyung-Ha Lee, Ki Hean Kim, Kyong-Tai Kim, Kyo Han Ahn
Rok vydání:	2013
Předmět:	chemistry.chemical_compound chemistry Two-photon excitation microscopy Process Chemistry and Technology General Chemical Engineering Fluorescence microscope Cationic polymerization Glutathione Azide Photochemistry Fluorescence Derivative (chemistry) Cysteine
Zdroj:	Dyes and Pigments. 99:308-315
ISSN:	0143-7208
DOI:	10.1016/j.dyepig.2013.05.008
Popis:	Two-photon probes for biothiols are developed based on arylsulfonyl azides for the first time. Thus, 6-(dimethylamino)naphthalene-2-sulfonyl azide and its triphenylphosphonium derivative undergo a fast reduction with turn-on fluorescence change by typical biothiols such as hydrogen sulfide, glutathione, cysteine, and homocysteine to produce the corresponding sulfonamides that is two-photon excitable. The cationic probe enables the selective imaging of the biothiols in mitochondria by two-photon fluorescence microscopy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::11107770c8bf6c6e6c4eb6184b126bd2 https://doi.org/10.1016/j.dyepig.2013.05.008 Zobrazit plný text záznamu Full Text from ScienceDirect