A continuous flow investigation of sulfonyl chloride synthesis using N-chloroamides: optimization, kinetics and mechanism

Autor: Dominik Polterauer, Dominique M. Roberge, Paul Hanselmann, Ryan Littich, Christopher A. Hone, C. Oliver Kappe
Rok vydání: 2022
Předmět:
Zdroj: Reaction Chemistry & Engineering. 7:2582-2592
ISSN: 2058-9883
DOI: 10.1039/d2re00280a
Popis: We develop a continuous flow protocol for the synthesis of sulfonyl chlorides from disulfides and thiols, using 1,3-dichloro-5,5-dimethylhydantoin (DCH) as a dual-function reagent for oxidative chlorination.
Databáze: OpenAIRE