Drug-induced Rowell syndrome in a male patient

Autor: Vessel Kantardjiev, Elena Stoikova, Valentina Broshtilova
Rok vydání: 2018
Předmět:
Zdroj: Scripta Scientifica Medica. 50:36
ISSN: 1314-6408
0582-3250
DOI: 10.14748/ssm.v50i4.5810
Popis: Rowell syndrome is a rare skin disease described as an association of erythema multiforme and systemic lupus erythematosus, immunologically characterized by speckled antinuclear, anti-Ro, and anti-La antibodies. The majority of described cases affect middle-aged women. We report a case of a 53-year-old man with no previous history of lupus erythematosus, who developed erythema multiforme-like lesions and immunological findings consistent with Rowell syndome upon an intake of non-steroidal anti-inflammatory drugs. The patient responded well to systemic steroids and hydroxychloroquine. A short overview, emphasizing the specific clinical, laboratory and histology findings of this peculiar syndrome, is also presented.
Databáze: OpenAIRE