Autor: |
Richard Leuking, Madhusudhanan Narasimhan, Lenin Mahimainathan, Alagar R Muthukumar, Yan Liu, Chao Xing, Christian P. Larsen, Andrew Clark, Jeffrey A. SoRelle |
Rok vydání: |
2022 |
DOI: |
10.1101/2022.04.04.22273058 |
Popis: |
Concomitant infection of multiple SARS-CoV-2 variants has become an increasing concern, as this scenario increases the likelihood of recombinant variants. Detecting co-infection of SARS-CoV-2 variants is difficult to detect by whole genome sequencing approaches, but genotyping methods facilitate detection. We describe 2 cases of Delta/Omicron and 2 cases of Omicron sublineage BA.1/ BA.2 co-infection as detected by a multiplex genotyping fragment analysis method. Findings were confirmed by whole genome sequencing. Review of the patient characteristics revealed co-morbidities and conditions which weaken the immune system and may make them more susceptible to harboring SARS-CoV-2 variant co-infections. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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