Improvement of silicone endothelialization by treatment with allylamine and/or acrylic acid low-pressure plasma
Autor: | Camille M. Kassis, Sophie Monge, Joseph M. DeSimone, Amina Hamzaoui, François Schué, André Mas |
---|---|
Rok vydání: | 2003 |
Předmět: |
Materials science
Polymers and Plastics Biocompatibility technology industry and agriculture 02 engineering and technology General Chemistry 010402 general chemistry 021001 nanoscience & nanotechnology Silicone rubber 01 natural sciences Plasma polymerization 0104 chemical sciences Surfaces Coatings and Films Allylamine chemistry.chemical_compound Silicone chemistry Polymer chemistry Materials Chemistry Polystyrene Wetting 0210 nano-technology Nuclear chemistry Acrylic acid |
Zdroj: | Journal of Applied Polymer Science. 87:1794-1802 |
ISSN: | 0021-8995 |
Popis: | Plasma polymerization of allylamine, acrylic acid, and an allylamine/acrylic acid mixture on Silastic® silicone rubber led to a strong increase in the silicone rubber's hydrophilicity and surface energy. Analysis of the deposited layer by X-ray photoelectron spectroscopy with 20° and 70° takeoff angles showed segregation of the atoms according to the depth and the incorporation of amino groups, oxygenated groups, and both. The endothelialization of untreated and treated samples was evaluated by the seeding and growth of aorta epithelial cells from pigs in cellular adherence (%), doubling time (in hours), and confluent density (104 cells/cm2). The best results were obtained with the allylamine/acrylic acid mixture treatment, which brought a biocompatibility to Silastic® similar to classic tissue culture on polystyrene plates. The interpretation was based on the presence of NH/CO2− microareas in the deposited layer. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 87: 1794–1802, 2003 |
Databáze: | OpenAIRE |
Externí odkaz: |