Interventionelle MR-Mammographie: Manipulatorgestützte Biopsie und interstitielle Lasertherapie von Tumoren der weiblichen Brust
| Autor: | Susanne Wurdinger, Christiane Marx, Stefan O.R. Pfleiderer, Jürgen R. Reichenbach, Werner A. Kaiser, Martin Freesmeyer, Achim Schneider, Harald Fischer, Jörg Vagner |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Breast biopsy
medicine.medical_specialty Radiological and Ultrasound Technology medicine.diagnostic_test business.industry Biophysics Interstitial laser Magnetic resonance imaging Ductal carcinoma medicine.disease Axilla medicine.anatomical_structure Breast cancer Biopsy Large core Medicine Radiology Nuclear Medicine and imaging Radiology business |
| Zdroj: | Zeitschrift für Medizinische Physik. 13:198-202 |
| ISSN: | 0939-3889 |
| DOI: | 10.1078/0939-3889-00164 |
| Popis: | The present study investigated the clinical application of magnetic resonance (MR)-guided breast interventions, such as manipulator-assisted large core breast biopsy (LCBB) inside a 1.5 T whole-body magnet and MR-guided interstitial laser therapy (ILT). Sixteen patients underwent LCBB and 1 additional patient underwent 4 sessions of ILT of a recurrent undifferentiated lymph node metastasis in the axilla using a Nd-YAG laser (1064 nm). Temperature changes of the tumor tissue during ILT were monitored using phase images of a gradient echo sequence (GRE) (TR/TE/FA = 25/12/30). In 5 patients the biopsy findings were histopathologically confirmed after open surgery. In 3 patients, the biopsy missed one tubular and one ductal carcinoma; one invasive carcinoma was underestimated. Eight patients with benign findings are still in the follow-up period. The heating zone during ILT was well delineated on subtracted phase images. No severe adverse events were observed with LCBB or ILT. MR-guided breast biopsies are feasible with the manipulator system inside a whole-body 1.5 Tesla MR scanner. GRE information is suitable for therapy monitoring during ILT within the tumor. Further studies are necessary to evaluate the accuracy of the manipulator system and the efficacy of ILT in the treatment of breast lesions. |
| Databáze: | OpenAIRE |
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