| Autor: | A. Kiss, I. Bodrogi, A. Határ, P. Szeldeli, J. Kondás, F. Törzsök, L. Kiss, T. Lukács |
|---|---|
| Rok vydání: | 1999 |
| Předmět: | |
| Zdroj: | International Urology and Nephrology. 31:451-456 |
| ISSN: | 0301-1623 |
| DOI: | 10.1023/a:1007155026151 |
| Popis: | We evaluated the prophylactic efficacy of instillations of intravesical mitomycin C in 57 patients with primary superficial bladder cancer in a multicenter clinical trial. After complete transurethral resection of Ta–T1 G1–G2 transitional cell bladder carcinomas, patients were treated with mitomycin 40 mg/50 ml saline of 15 instillations for 12 months. Most of the complications were mild and transient but two patients dropped out of the trial because of moderate side effects. Fifty-one patients were evaluable. We observed tumour recurrences in six patients (11.8%) during a median follow-up of 44.5 months. The recurrences were treated by transurethral resection. There was no muscle invasive progression in the recurrences. Our investigations confirm the effectiveness of mitomycin C in the treatment of patients with superficial bladder cancer. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink