Popis: |
This study deals with the tissue response of the incised rat tongue to three chemical adhesives—hexyl, heptyl, and octyl cyanoacrylates. Sixty-three rats were divided into three groups, their tongues were incised and approximated with these materials, and the animals were killed 1, 3, 5, 10, 14, 21, and 30 days postoperatively. Histologic analysis revealed the following: 1. 1. The tissue receptivity of the three adhesive materials was almost identical. 2. 2. The hexyl, heptyl, and octyl cyanoacrylates did not appear to be superior to the butyl cyanoacrylate. 3. 3. The rat tongues, showed the normal healing process, and the adhesive material was gradually removed from the site of application. This removal was brought about partly by sequestration and partly by phagocytosis. The material which persisted in the tissues was completely surrounded by histiocytes and foreign body giant cells. |