Peripheral nerve high-resolution ultrasound in diabetes
| Autor: | Ari Breiner, Alon Abraham, Bruce A. Perkins, Majed Alabdali, Leif E. Lovblom, Mohammad Qrimli, Vera Bril, Hamid Ebadi, Hana Albulahi |
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| Rok vydání: | 2016 |
| Předmět: |
medicine.medical_specialty
Diabetic neuropathy Physiology business.industry Ultrasound Urology High resolution ultrasound medicine.disease 030218 nuclear medicine & medical imaging Peripheral 03 medical and health sciences Cellular and Molecular Neuroscience 0302 clinical medicine stomatognathic system Peripheral nerve Physiology (medical) Diabetes mellitus Healthy volunteers medicine In patient Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Muscle & Nerve. 55:171-178 |
| ISSN: | 0148-639X |
| DOI: | 10.1002/mus.25223 |
| Popis: | Introduction High-resolution ultrasound (HRU) is used in the diagnosis of peripheral neuropathies. There are conflicting data regarding HRU findings in patients with diabetic sensorimotor polyneuropathy (DSP). Our purpose in this study was to measure nerve cross-sectional areas (CSAs) in patients with diabetes, with and without DSP. Methods We performed a prospective peripheral nerve HRU study of 100 diabetic subjects, assessed the CSA at predefined sites, and compared the results with those of 100 normal subjects. We evaluated the use of individual CSA values and various summary scores for diagnosis of DSP. Results Diabetic subjects had higher CSA values than healthy volunteers, and those with DSP had higher CSA values. Three or more enlarged CSA sites predicted DSP with 64% sensitivity and 77% specificity. Conclusions Peripheral nerves are enlarged diffusely in diabetic patients, including sites not susceptible to bony compression. The number of enlarged CSA values can help predict the presence of DSP. Muscle Nerve, 2016 Muscle Nerve 55: 171-178, 2017. |
| Databáze: | OpenAIRE |
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