Characterization of breast lesion morphology with delayed 3DSSMT: An adjunct to dynamic breast MRI

Autor: Robert J. Herfkens, Cindy S. Leong, Anne M. Sawyer-Glover, Stefanie S. Jeffrey, Gary H. Glover, Debra M. Ikeda, Bruce L. Daniel, Robyn L. Birdwell
Rok vydání: 2000
Předmět:
Zdroj: Journal of Magnetic Resonance Imaging. 11:87-96
ISSN: 1522-2586
1053-1807
DOI: 10.1002/(sici)1522-2586(200002)11:2<87::aid-jmri3>3.0.co;2-e
Popis: The purpose of the study was to determine the sensitivity and specificity of various morphologic criteria in distinguishing malignant from benign breast lesions using a new sequence (3DSSMT) performed immediately after dynamic breast MRI. 3DSSMT combines a water-selective spectral-spatial excitation and an on-resonance magnetization transfer pulse with three-dimensional spoiled gradient-echo imaging. Morphologic features of 87 pathologically confirmed lesions were analyzed. The presence of either skin thickening, or a combination of a spiculated or microlobulated border, with a rim, ductal, linear, or clumped enhancement pattern was 94% specific and 54% sensitive for malignancy. Conversely, the presence of either a perfectly smooth border, a well-defined margin, non-enhancing internal septations, or a macrolobulated border was 97% specific and 35% sensitive for a benign diagnosis. In conclusion, delayed 3DSSMT discriminates a significant number of benign and malignant breast lesions; it has the potential to improve the diagnostic accuracy of dynamic breast MRI. J. Magn. Reson. Imaging 2000;11:87–96. © 2000 Wiley-Liss, Inc.
Databáze: OpenAIRE
Externí odkaz: