Optic Neuropathy Due to Chronic Lymphocytic Leukemia Proven With Optic Nerve Sheath Biopsy
| Autor: | Patricia Chévez-Barrios, Michael L. Morgan, Sushma Yalamanchili, Amina I. Malik, Khurrum Khan, Sumayya J. Almarzouqi, Andrew G. Lee |
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| Rok vydání: | 2016 |
| Předmět: |
Pathology
medicine.medical_specialty genetic structures Chronic lymphocytic leukemia Central nervous system Optic neuropathy 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine immune system diseases hemic and lymphatic diseases Biopsy medicine Papilledema medicine.diagnostic_test business.industry medicine.disease eye diseases Ophthalmology Leukemia medicine.anatomical_structure chemistry 030220 oncology & carcinogenesis Ibrutinib 030221 ophthalmology & optometry Optic nerve Neurology (clinical) medicine.symptom business |
| Zdroj: | Journal of Neuro-Ophthalmology. 36:61-66 |
| ISSN: | 1070-8022 |
| DOI: | 10.1097/wno.0000000000000300 |
| Popis: | Central nervous system involvement from chronic lymphocytic leukemia (CLL) occurs infrequently, and manifestations include cognitive and cerebellar dysfunction and cranial nerve palsies. We report a 45-year-old man with CLL believed to be in clinical remission, who presented with vision loss and bilateral optic disc edema. His optic neuropathy due to CLL was proven by optic nerve sheath biopsy, and he experienced visual recovery after treatment with ibrutinib and intrathecal methotrexate. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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