The influence of pressor and depressor substances on the greater and lesser circulations in hypoxic hypoxia
| Autor: | K. N. Fedorova |
|---|---|
| Rok vydání: | 1963 |
| Předmět: |
Tachycardia
medicine.medical_specialty Chemistry Hypoxic hypoxia General Medicine Hypoxia (medical) medicine.disease General Biochemistry Genetics and Molecular Biology Endocrinology Hypocapnia Greater circulation Internal medicine Heart rate medicine Serotonin medicine.symptom Acetylcholine medicine.drug |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 53:27-31 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf00794704 |
| Popis: | A study was made of the effect produced by 0.7 μg/kg adrenalin, 5–10 μg/kg acetylcholine, and 10–15 μg/kg serotonin on the greater and lesser circulations in hypoxia accompanied by hypocapnia, and in hypoxia during normal breathing. It was shown that the depressor response in the greater circulation and the tachycardia induced by acetylcholine were increased by hypoxia. Elimination of the hypocapnia enhanced the depressor action induced by acetylcholine, but increased the heart rate less. In oxygen lack, sensitivity to adrenalin and serotonin was reduced. The pressor reactions induced by adrenalin increased during hypoxia, and after elimination of hypocapnia, in many cases the control level was attained. It appears that the reduction of sensitivity to adrenalin in hypoxia depends mainly not on the hypoxia itself but on the associated hypocapnia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink