Stereoselective approach to conjugated enone oximes from aliphatic nitro compounds and sulfur ylides

Autor:	Alexey Yu. Sukhorukov, Sema L. Ioffe, Rauf T. Akhmirov
Rok vydání:	2021
Předmět:	chemistry.chemical_classification chemistry.chemical_compound Silylation chemistry Ylide Nitro chemistry.chemical_element Stereoselectivity General Chemistry Conjugated system Medicinal chemistry Sulfur Enone
Zdroj:	Mendeleev Communications. 31:686-689
ISSN:	0959-9436
DOI:	10.1016/j.mencom.2021.09.031
Popis:	A novel approach to conjugated enone oximes from aliphatic nitro compounds deals with double silylation of N,N-bis(silyloxy) enamines followed by a stereoselective reaction with an ester-stabilized sulfur ylide. The proposed mechanism involves the generation of labile nitrosoalkenes as intermediates, which react with the sulfur ylide to give target enone oximes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::108588305187320f3e9d1bd3039779ac https://doi.org/10.1016/j.mencom.2021.09.031 Zobrazit plný text záznamu Full Text from ScienceDirect