Case-Control Studies in Aging Research

Autor: Laura Bárbara Velázquez-Olmedo, Ángel Cárdenas-Bahena, Sergio Sánchez-García, Erika Heredia-Ponce, Carmen García-Peña, Luis Pablo Cruz-Hervert
Rok vydání: 2018
Předmět:
Zdroj: Aging Research-Methodological Issues ISBN: 9783319953861
DOI: 10.1007/978-3-319-95387-8_7
Popis: In the planning phase of research related to age and aging, the quality of knowledge derived from epidemiological studies, depends heavily on the solidity of the methodological design and the strategies for collecting data designed to answer the research question. The classic design of case-control studies distinguishes between older adults who have a specific outcome or disease (cases) and those who do not (controls) and are determines whether the subjects were exposed or not to one or several factors to try to establish, retrospectively (that is, from the effect to the cause), the relationship of these factors with the disease. Case-control studies are a cost-effective alternative for providing a valid and reasonably precise estimate for identifying an association force of a hypothetical relationship cause-effect in studies related to older adults. Recently case-control studies have been related directly to cohort studies, which enabled researchers to design new patterns for their development while obtaining major benefits. The case-control study is the appropriate choice and at times the only alternative for studying diseases of very low incidence in older adults. With this type of study, it is possible to explore a broad range of related exposures to illness. Another important advantage is that they require smaller samples and are less costly than experimental designs or cohort studies. Among the disadvantages or drawbacks of this type of study is that it can only provide information about the event or target disease in the population that has been selected for carrying out the study.
Databáze: OpenAIRE