Evaluation of the effects of dexmedetomidine and remifentanil on pain with the analgesia nociception index in the perioperative period in hysteroscopies under general anesthesia
| Autor: | Fatma Nur Akgün, Güldem Turan, Dilek Erdoğan Arı, Süheyla Abitağaoğlu, Mustafa Gazi, Ceren Köksal |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
medicine.diagnostic_test
business.industry Visual analogue scale Remifentanil General Medicine Perioperative Sevoflurane 03 medical and health sciences 0302 clinical medicine 030202 anesthesiology Hysteroscopy Bispectral index Anesthesia medicine Dexmedetomidine business Prospective cohort study 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Saudi Medical Journal. 39:1017-1022 |
| ISSN: | 1658-3175 0379-5284 |
| Popis: | Objectives To compare analgesia nociception index (ANI) values, visual analog scale (VAS) values, and hemodynamic parameters in hysteroscopy patients who received remifentanil and dexmedetomidine during general anesthesia. Methods : In total, 30 patients who underwent hysteroscopy between March and September 2016 at the University of Health Sciences Fatih Sultan Mehmet Health Research and Application Center, Ankara, Turkey were included in this prospective study. Standard hemodynamic monitoring, ANI, and bispectral index (BIS) monitoring were applied to the patients. At 10 min prior to induction, 1 μg/kg of remifentanil was applied in Group R (n=15) and 1 μg/kg of dexmedetomidine was applied in Group D (n=15). After induction, sevoflurane was used for maintenance with dexmedetomidine at 0.2-0.7 μg/kg/hour in Group D and remifentanil at 0.05-0.5 μg/kg/minute in Group R. Perioperative and postoperative analgesia levels (ANI and VAS, respectively), hemodynamics, and complications were recorded. Results : Even though the ANI levels in Group D were lower at the perioperative 5th and 10th minutes, the ANI values were between the targeted limits, except for the measurement after I-gel insertion, in both groups. Hemodynamic parameters were within normal limits, but the mean arterial pressures in Group R after induction, following I-gel placement, and at the perioperative 5th, 10th, and 20th minutes and postoperative 30th minute were significantly higher. Conclusion : Dexmedetomidine and remifentanil are both efficacious agents for perioperative analgesia in hysteroscopy cases. Saudi Med J 2018; Vol. 39 (10): 1017-1022 doi: 10.15537/smj.2018.10.23098 How to cite this article: Gazi M, Abitagaoglu S, Turan G, Koksal C, Akgun FN, Ari DE. Evaluation of the effects of dexmedetomidine and remifentanil on pain with the analgesia nociception index in the perioperative period in hysteroscopies under general anesthesia. A randomized prospective study. Saudi Med J . 2018 Oct;39(10):1017-1022. doi: 10.15537/smj.2018.10.23098. |
| Databáze: | OpenAIRE |
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