Effect of gamma sterilization on Gymnema sylvestre leaf extract fused Polycaprolactone nanofiber for effective wound dressing applications
| Autor: | Sundarapandian Subramanian, Mohammed Junaid Hussain Dowlath, Shazia Anjum Musthafa, Sathish Kumar Karuppannan, Ganesh Munuswamy-Ramanujam, S.B. Mohamed Khalith, Kantha Deivi Arunachalam, V. Chitra, Raghavendra Ramalingam |
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| Rok vydání: | 2021 |
| Předmět: |
Materials science
integumentary system Mechanical Engineering 02 engineering and technology Sterilization (microbiology) 010402 general chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics 01 natural sciences 0104 chemical sciences Wound care chemistry.chemical_compound medicine.anatomical_structure chemistry Mechanics of Materials Wound dressing Nanofiber Polycaprolactone medicine General Materials Science 0210 nano-technology Fibroblast Wound healing Antibacterial activity Biomedical engineering |
| Zdroj: | Materials Letters. 300:130145 |
| ISSN: | 0167-577X |
| DOI: | 10.1016/j.matlet.2021.130145 |
| Popis: | Nanomaterials have been proven to speed up wound healing compared to other wound healing materials. In the present study, Gymnema sylvestre leaf extract was incorporated into polycaprolactone (PCL) nanofiber, gamma sterilized and used for efficient wound dressing applications. The synthesized nanofibers (NFs) were beadless, hydrophilic, and continuous, exhibited surface mediated antibacterial activity against wound pathogens and enhanced proliferation of fibroblast cells. The fabricated NFs can be constructively used for wound care application. |
| Databáze: | OpenAIRE |
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