Super arming of a glycosyl donor using a molecular lever

Autor: Christian Pedersen, Jacob Ingemar Olsen, Karolina Kowalska, Mikael Bols
Rok vydání: 2016
Předmět:
Zdroj: Tetrahedron Letters. 57:35-38
ISSN: 0040-4039
Popis: Novel thiomannosyl donors with a 2,3-(phenyl-1,2-ethylidine) tethering group were designed so that the phenyl group would act as a molecular lever and force the pyranoside into its most reactive conformation. It was demonstrated that this type of molecular leverage could increase the reaction rate at least 200 times.
Databáze: OpenAIRE