Super arming of a glycosyl donor using a molecular lever
Autor: | Christian Pedersen, Jacob Ingemar Olsen, Karolina Kowalska, Mikael Bols |
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Rok vydání: | 2016 |
Předmět: | |
Zdroj: | Tetrahedron Letters. 57:35-38 |
ISSN: | 0040-4039 |
Popis: | Novel thiomannosyl donors with a 2,3-(phenyl-1,2-ethylidine) tethering group were designed so that the phenyl group would act as a molecular lever and force the pyranoside into its most reactive conformation. It was demonstrated that this type of molecular leverage could increase the reaction rate at least 200 times. |
Databáze: | OpenAIRE |
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