Carbon nanotube field effect transistor aptasensors for estrogen detection in liquids
| Autor: | Cameron S. Wood, Han Yue Zheng, Omar A. Alsager, Justin M. Hodgkiss, Natalie O. V. Plank |
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| Rok vydání: | 2015 |
| Předmět: |
Materials science
Process Chemistry and Technology Aptamer Nanotechnology Carbon nanotube Surfaces Coatings and Films Electronic Optical and Magnetic Materials law.invention Carbon nanotube field-effect transistor symbols.namesake Nanolithography law Nanosensor Materials Chemistry symbols Surface modification Field-effect transistor Electrical and Electronic Engineering Instrumentation Debye length |
| Zdroj: | Journal of Vacuum Science & Technology B, Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena. 33:06F904 |
| ISSN: | 2166-2754 2166-2746 |
| DOI: | 10.1116/1.4935246 |
| Popis: | The authors demonstrate a small molecule 17 β-estradiol (E2) sensor based on aptamer functionalized carbon nanotube network film field effect transistors (CNT FETs). The real time current response for the 35-mer E2 aptamer functionalized CNT FET shows a clear increase in current over the range of 50 nM to 1.6 μM of E2. The E2 response using a longer 75-mer version of the aptamer functionalized CNT FETs, where the aptamer/E2 binding occurs beyond the Debye length, shows no obvious evidence of sensing. The CNT FET sensing platform has been fabricated via a simple surfactant free solution processing route, compatible with further carbon nanotube functionalization to develop a versatile sensing platform. The CNT FET aptasensors are able to perform real time monitoring of E2 levels for selective and quantitative detection of E2 in liquids. |
| Databáze: | OpenAIRE |
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