STUDIES ON THE RELATIONSHIP OF THE SEX HORMONES TO INFECTION II. THE EFFECT OF PSEUDOPREGNANCY ON THE SPREAD OF INDIA INK IN THE SKIN OF RABBITS

Autor:	Douglas H. Sprunt, Sara McDearman
Rok vydání:	1939
Předmět:	medicine.medical_specialty Pregnancy Fetus Myxomatosis Estrone Biology medicine.disease Virus chemistry.chemical_compound Endocrinology medicine.anatomical_structure chemistry Internal medicine Placenta medicine Vaccinia Hormone
Zdroj:	Endocrinology. 25:308-311
ISSN:	1945-7170 0013-7227
DOI:	10.1210/endo-25-2-308
Popis:	SEVERAL YEARS ago one of us (i) reported that pregnancy in rabbits altered the reactivity of the tissues to the virus of infectious myxomatosis. In the first paper of this series (2) we showed that the injection of estrone into castrated male rabbits decreased the spread of India ink in the skin and also increased the rabbits'resistance to infection with vaccinia. These papers together with the literature indicate that variations in the sex hormones can cause modification in the susceptibility of the rabbit to infection. This fact seemed of sufficient importance to warrant further study. In the present experiment we have thought it desirable to learn more concerning the spread of materials in the normal animal before continuing the study of changes produced by the injection of the various hormones. Pseudopregnancy in the rabbit offered an excellent opportunity for this study, since it is not complicated by the presence of a fetus and a placenta
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::1043553d316d0871d4eceaf4e2a86d08 https://doi.org/10.1210/endo-25-2-308 Zobrazit plný text záznamu