The Correlation Analysis on Glycolipid Metabolism, CysC and Homocysteine of Thyroid Dysfunction
| Autor: | Fan Hong, Hou Jianzhang, Zhang Jingyu, Hou Zhenjiang, Rongqin Dai, Wang Hongsheng |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
endocrine system
medicine.medical_specialty endocrine system diseases biology Homocysteine business.industry medicine.medical_treatment Organic Chemistry Thyroid Blood lipids Lipid metabolism Biochemistry Thyroid carcinoma chemistry.chemical_compound Endocrinology medicine.anatomical_structure Cystatin C Thyroid-stimulating hormone chemistry Internal medicine biology.protein Medicine lipids (amino acids peptides and proteins) Thyroglobulin business |
| Zdroj: | Science Journal of Public Health. 6:55 |
| ISSN: | 2328-7942 |
| DOI: | 10.11648/j.sjph.20180602.14 |
| Popis: | The objective is to discuss about the correlation of Glycolipid Metabolism, Cystatin C (CysC) and Homocysteine (Hcy) of thyroid dysfunction. 100 cases of hyperthyroidism, hypothyroidism and the control group are chose respectively to measure Fiber Bragg Grating (FBG), Blood Lipid, Thyroid Hormone (TH), CysC and Hcy, calculate the blood lipid ratio and make analysis. As a result, Thyroid Carcinoma (TC), Thyroglobulin (TG), Low-density Lipoprotein Cholesterol (LDL-C), High-density Lipoprotein Cholesterol (HDL-C), TC/HDL-C, TG/HDL-C, LDL-C/HDL-C, Lipid comprehensive index (LCI) and non-HDL-C of hyperthyroidism group are obviously lower than the control group. The decrease of LCI is the most prominent. Hcy is slightly lower than the control group. FBG and CysC are obviously higher than the control group. TC, TG, LDL-C, TG/HDL-C, LDL-C/HDL-C, LCI and non-HDL-C, Hcy of hypothyroidism group are higher than the control group (P＜0.05), and FBG, HDL-C and CysC are lower than the control group (P＜0.05). Various kinds of TH have the highest connection with TC, followed by non-HDL-C, LDL-C and LCI. It comes to the conclusion that patients with thyroid dysfunction easily appear the disorder of glucose and lipid metabolism. The change in blood lipid ratio is more pronounced than that of single lipid indicator and is closely related to CysC and Hcy. Dynamic monitoring of Thyroid Stimulating Hormone (TSH), blood lipid ratio, CysC and Hcy is of great value in the diagnosis of thyroid dysfunction and the prediction of Cardiovascular Disease (CVD) in concurrent Coronary Heart Disease (CHD) and so on. |
| Databáze: | OpenAIRE |
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