Synthesis and Immunomodulating Activity of New Amino Acid Derivatives of Glycyrrhizic Acid and Its Methyl Ester

Autor:	R. M. Kondratenko, L. A. Baltina, E. V. Vasil'eva, Kh. M. Nasyrov, R. M. Kireeva, N. Zh. Baschenko, S. M. Fridman, L. A. Baltina (Jr. ), G. A. Tolstikov
Rok vydání:	2004
Předmět:	Alanine chemistry.chemical_classification Blood serum Chemistry Organic Chemistry Organic chemistry Bioorganic chemistry Hemolysin Glycine ethyl ester Biochemistry Amino acid
Zdroj:	Russian Journal of Bioorganic Chemistry. 30:148-153
ISSN:	1068-1620
DOI:	10.1023/b:rubi.0000023100.52170.6b
Popis:	New amino acid derivatives of glycyrrhizic acid and its methyl ester were selectively synthesized using active N-succinimide esters. The compounds with residues of glycine ethyl ester and alanine methyl and butyl esters increased the level of agglutinins and hemolysins in blood serum of mice two- to threefold in comparison with the control upon parenteral administration at a dose of 2 mg/kg for 14 days.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0ff482400810149cfbf2752810acacf1 https://doi.org/10.1023/b:rubi.0000023100.52170.6b Zobrazit plný text záznamu Full text from SpringerLink