Alteration in plasma levels of nonprotein sulfhydryl compounds and S-nitrosothiols in chronic renal failure patients
| Autor: | Adam Markiewicz, Maria Sokołowska, Przemysław J Włodek, Andrzej Miłkowski, Justyna Kucharczyk, Lidia Włodek, Olgierd B Smolenski |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Chemistry medicine.medical_treatment Biochemistry (medical) Clinical Biochemistry General Medicine Glutathione Malondialdehyde medicine.disease Biochemistry Uremia Nitric oxide chemistry.chemical_compound NPSH Endocrinology Internal medicine medicine Thiol Hemodialysis Dialysis |
| Zdroj: | Clinica Chimica Acta. 327:87-94 |
| ISSN: | 0009-8981 |
| Popis: | Background: Uremia is accompanied by the elevated nitric oxide (NO) synthesis, and it has not yet been established how this influences the levels of nonprotein sulfhydryl compounds (NPSH) and formation of S-nitrosothiols (SNT). Methods: Our study was designed to determine plasma levels of SNT and NPSH in chronic renal failure (CRF) patients, who were hemodialysed (HD) or were not on hemodialysis treatment (ND), and in the control group. Results: In ND patients, the plasma levels of SNT were significantly increased (11.25±2.08 nmol/ml, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect