Synthesis, characterization,in silicomolecular docking, and antibacterial activities of some new nitrogen-heterocyclic analogues based on ap-phenolic unit
| Autor: | Abdel Haleem M. Hussein, Abu-Bakr A. El-Adasy, Ahmed M. El-Saghier, M. Olish, Aboubakr H. Abdelmonsef |
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| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | RSC Advances. 12:12607-12621 |
| ISSN: | 2046-2069 |
| DOI: | 10.1039/d2ra01794f |
| Popis: | Compounds 6a and 6b (with pyrimidine moiety, amide linkage, and phenolic substrate) might be potent bacterial flavohemoglobin (flavoHB) inhibitors and they could set a promising starting point for future design of antibacterial agents. |
| Databáze: | OpenAIRE |
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