Autor: |
M Berger, N Rehm, U Dobrindt |
Rok vydání: |
2016 |
Předmět: |
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DOI: |
10.1016/b978-0-12-800049-6.00236-5 |
Popis: |
The ability of bacteria to successfully colonize a niche and to adapt to varying growth conditions relies in large parts on bacterial genome plasticity. The gain and loss of horizontally acquired genetic information as well as point mutations, intragenomic rearrangements, and large gene amplifications contribute to genomic variability. The chromosomal structure and organization can affect the efficient incorporation of foreign DNA into the chromosome and also gene expression. Genome plasticity should not only be perceived as alterations of genome content. Structural constraints affecting the accessibility and expression of genomic loci shape bacterial genomes and are thus involved in bacterial evolution. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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