Human Immunodeficiency Virus II: Clinical Presentation, Opportunistic Infections, Treatment, and Prevention
Autor: | Simi Padival, Ami Multani, Bradford Becken |
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Rok vydání: | 2019 |
Předmět: |
medicine.medical_specialty
business.industry Transmission (medicine) medicine.medical_treatment Human immunodeficiency virus (HIV) Immunosuppression medicine.disease_cause medicine.disease Antiretroviral therapy Immune system New medications Acquired immunodeficiency syndrome (AIDS) medicine business Intensive care medicine Viral load |
Zdroj: | Introduction to Clinical Infectious Diseases ISBN: 9783319910796 |
DOI: | 10.1007/978-3-319-91080-2_41 |
Popis: | Uncontrolled HIV infection eventually leads to acquired immunodeficiency syndrome (AIDS), a state of severe immunosuppression which allows for other opportunistic infections or malignancies to be acquired. There is a high morbidity and mortality associated with sustained, elevated HIV viral loads; however, access to and treatment with antiretroviral therapy (ART) reduce the morbidity substantially. Combination antiretroviral therapy has been shown to improve immune function, reduce HIV reservoirs, and reduce transmission of HIV infection to others. While a cure for HIV remains elusive, new medications and novel medication classes have greatly simplified treatment, improving the quality of life of those affected and dramatically decreasing transmission rates. Antiretroviral medications are also now used for pre-exposure prophylaxis among individuals at high risk as one of the key components of reducing transmission. |
Databáze: | OpenAIRE |
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