Human Immunodeficiency Virus II: Clinical Presentation, Opportunistic Infections, Treatment, and Prevention

Autor: Simi Padival, Ami Multani, Bradford Becken
Rok vydání: 2019
Předmět:
Zdroj: Introduction to Clinical Infectious Diseases ISBN: 9783319910796
DOI: 10.1007/978-3-319-91080-2_41
Popis: Uncontrolled HIV infection eventually leads to acquired immunodeficiency syndrome (AIDS), a state of severe immunosuppression which allows for other opportunistic infections or malignancies to be acquired. There is a high morbidity and mortality associated with sustained, elevated HIV viral loads; however, access to and treatment with antiretroviral therapy (ART) reduce the morbidity substantially. Combination antiretroviral therapy has been shown to improve immune function, reduce HIV reservoirs, and reduce transmission of HIV infection to others. While a cure for HIV remains elusive, new medications and novel medication classes have greatly simplified treatment, improving the quality of life of those affected and dramatically decreasing transmission rates. Antiretroviral medications are also now used for pre-exposure prophylaxis among individuals at high risk as one of the key components of reducing transmission.
Databáze: OpenAIRE