High cholesterol diet supplemented with sunflower seed oil but not olive oil stimulates lipid peroxidation in plasma, liver, and aorta of rats
| Autor: | Muzaffer Öztürk, Gülçin Toker, Gül Özdemirler, Müjdat Uysal, Buge Oz, Hüseyin Bulur |
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| Rok vydání: | 1995 |
| Předmět: |
medicine.medical_specialty
food.ingredient Endocrinology Diabetes and Metabolism Clinical Biochemistry Biology Biochemistry Lipid peroxidation chemistry.chemical_compound food medicine.artery Internal medicine medicine Food science Molecular Biology chemistry.chemical_classification Aorta Nutrition and Dietetics Lipid peroxide Cholesterol Sunflower oil Cholic acid Endocrinology chemistry lipids (amino acids peptides and proteins) Sunflower seed Polyunsaturated fatty acid |
| Zdroj: | The Journal of Nutritional Biochemistry. 6:547-550 |
| ISSN: | 0955-2863 |
| Popis: | To determine the effect of a high cholesterol diet supplemented with sunflower seed oil or olive oil on plasma, liver, and aorta lipid peroxidation, rats were fed a basal diet, a high cholesterol diet (basal diet containing 2% cholesterol and 0.5% cholic acid), or a high cholesterol diet supplemented with 10% ( wt wt ) sunflower seed oil or 10% ( wt wt ) olive oil for 4 months. In rats fed the high cholesterol diet supplemented with sunflower seed oil, plasma, liver, and aorta lipid peroxide levels and the aorta cholesterol to phospholipid ratio were greater than in rats fed the high cholesterol diet. In contrast, no change was observed in plasma, liver, and aorta lipid peroxidation and the cholesterol to phospholipid ratio in rats fed the high cholesterol diet containing olive oil as compared with the high cholesterol diet. In addition, atherosclerotic lesions were not detected in the aorta of all groups. We concluded that a high cholesterol diet supplemented with polyunsaturated fats, but not with monounsaturated fats, seems to have a tendency to exaggerate lipid peroxidation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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