Aqueous extracts of Flacourtia indica, Swartzia madagascariensis and Ximenia caffra are strong antibacterial agents against Shigella spp., Salmonella typhi and Escherichia coli O157

Autor: Constance Chingwaru, Walter Chingwaru, Tanja Bagar
Rok vydání: 2020
Předmět:
Zdroj: South African Journal of Botany. 128:119-127
ISSN: 0254-6299
Popis: Aqueous extraction methods, particularly steeping in hot water, are frequently adopted as methods of choice in traditional medicine (TM). Moreover, other more modern extraction methods tend to utilise sophisticated tools and a number of organic solvents. Unfortunately, the comparative value of the aqueous extraction methods as used in traditional medicine in relation to the other methods has remained largely undocumented. This study sought to establish the comparative antimicrobial activities and composition of Flacourtia indica bark, Swartzia madagascariensis leaf and Ximenia caffra leaf extracts obtained using (i) hot water extraction (THWE), (ii) cold water extraction (CWEC) and (iii) ethanolic extraction (EEC) methods against putative isolates of Shigella spp., Salmonella typhi and Escherichia coli O157. Bacteriostatic and bactericidal effects of the extracts were determined using the standard well diffusion assay. The hot water extracts (THWE) and the cold water extracts (desiccated) (CWEC) were shown to have significantly greater inhibitory activities then the ethanolic extracts (EEC) (desiccated) against Shigella spp. and S. typhi (p
Databáze: OpenAIRE