Determination of zolpidem and its metabolites by chromatography-mass spectrometry

Autor:	S. S. Kataev, Yu. A. Khomov, E. A. Krylova
Rok vydání:	2013
Předmět:	Zolpidem Chromatography Chemistry musculoskeletal neural and ocular physiology Extraction (chemistry) medicine Solid phase extraction Gas chromatography Mass spectrometry psychological phenomena and processes Analytical Chemistry medicine.drug
Zdroj:	Journal of Analytical Chemistry. 68:722-729
ISSN:	1608-3199 1061-9348
DOI:	10.1134/s1061934813080066
Popis:	Conditions of the simultaneous isolation of various types of zolpidem metabolites from samples of real urine by solid-phase extraction have been optimized. Various derivatives of zolpidem hydroxy- and carboxy-metabolites were obtained; their mass-spectral and gas-chromatographic characteristics have been studied. The results ensure the reliable identification of zolpidem metabolites by gas chromatography-mass spectrometry for chemical toxicological and forensic investigations.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0f55a0ed67d08d53b44f5df9e8c629e4 https://doi.org/10.1134/s1061934813080066 Zobrazit plný text záznamu Plný text ve formátu PDF