| Autor: |
Slobodian S.О., Gutyj B.V., Leskiv Kh.Ya., Khariv, I.I., Paziuk I., S. |
| Rok vydání: |
2020 |
| Předmět: |
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| DOI: |
10.24412/2520-2480-2020-3082-20-24 |
| Popis: |
Lead and cadmium are among the influential environmental pollutants today. The results of many experi-mental studies indicate that in mammals Cadmium and Lead have a toxic effect on many organs and systems. The research aimed to study the impact of sodium selenite and feed additive “Metisevit Plus” on the morpho-logical parameters of the blood of rats under cadmium and lead intoxication. The analyses were performed on male Wistar rats weighing 200–220 g, from which 3 groups of animals were formed: control (C) and two exper-imental (E1), (E2). Mice of the (C) and (E1), (E2) groups were injected with 16.6% lead acetate aqueous solution at a dose of 100 mg/kg and 0.029% cadmium chloride aqueous solution at a dose of 2.0 mg/kg. Rats of the (E1) group were additionally administered sodium selenite at a dose of 0.2 mg/kg body weight. Animals of the (E2) group were additionally given a feed additive “Metisevit plus” at a dose of 0.5 mg/kg body weight. Sodium selenite and feed additive “Metisevit plus” contributes to the normalization of morphological parameters of the blood in spite of the development of chronic lead-cadmium toxicosis. However, it should be noted that the better normalizing effect of the blood is feed additive “Metisevit Plus” on the morphological parameters of the blood than the sodium selenite in animals. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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