ExperimentalMicrosporum canisinfection in cats: correlation between immunological and clinical observations
| Autor: | AH Sparkes, Timothy J Gruffydd-Jones, C. R. Stokes |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
Cellular immunity
Pathology medicine.medical_specialty CATS medicine.diagnostic_test Physical examination General Medicine Biology medicine.disease_cause medicine.disease biology.organism_classification Lesion Infectious Diseases Dermatophyte medicine Carnivora Microsporum canis medicine.symptom Mycosis |
| Zdroj: | Medical Mycology. 33:177-184 |
| ISSN: | 1460-2709 1369-3786 |
| Popis: | Microsporum canis infection was induced in five of six adult cats by the application of mycelium to shaved and mildly abraided skin. The clinical course of the disease was monitored over 16 weeks by physical examination and Wood's lamp illumination. The inclubation period (time from inoculation to first appearance of infected hairs) varied between 8 and 13 days and was followed by a progressive phase of slow peripheral expansion of lesions accompanied by scaling, alopecia and skin thickening that lasted for approximately 2 weeks. In four of the five cats the lesions then remained stable for between 1 and 6 weeks before regression occurred, with clinical resolution evident in these cats by 11–14 weeks post-infection. In one cat disease was more prolonged, with regression only beginning at the end of the study, and this cat also developed a satellite lesion. Immunological responses during infection were monitored every 2 weeks and consisted of ELISA to measure serum M. canis-specific IgG, IgM and IgA antibo... |
| Databáze: | OpenAIRE |
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