Synthesis of optically active 3-oxa-carbacyclin precursors featuring asymmetric Horner-Emmons reaction

Autor:	Irene Erdelmeier, Jörg Bund, Gerhard Schmiedl, Gunther Hellmann, Hans-Joachim Gais, Walter A. Ball
Rok vydání:	1988
Předmět:	chemistry.chemical_classification Allylic rearrangement Ketone Bicyclic molecule Chemistry Stereochemistry Organic Chemistry Enantioselective synthesis Optically active Primary alcohol Biochemistry Phosphonate chemistry.chemical_compound Drug Discovery Organic chemistry
Zdroj:	Tetrahedron Letters. 29:1773-1774
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(00)82039-0
Popis:	An enantioselective synthesis of 5 is described. Asymmetric Horner-Emmons reactions with the chiral phosphonate 6 are key steps in the synthesis of the allylic alcohols E - 8 and E - 11 from the ketones 5 and 9, respectively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0efc09a3c1a4b7e06e5ef23d440c7858 https://doi.org/10.1016/s0040-4039(00)82039-0 Zobrazit plný text záznamu