Combined motion blur and partial volume correction for computer aided diagnosis of pulmonary nodules in PET/CT

Autor: Ralph Buchert, Timo Paulus, Rafael Wiemker, Sven Kabus, Susanne Klutmann, Ivayla Apostolova, Thomas Bülow
Rok vydání: 2008
Předmět:
Zdroj: International Journal of Computer Assisted Radiology and Surgery. 3:105-113
ISSN: 1861-6429
1861-6410
DOI: 10.1007/s11548-008-0212-y
Popis: Objective We present an automated scheme to correct PET max-uptake-values of small to medium-sized pulmonary nodules for motion blur and partial volume averaging. Both effects cause significant underestimation of PET max-uptake-values, particularly in nodules below 25 mm diameter, but nodules up to 75 mm might be affected. This compromises the power of PET for the differential diagnosis of such nodules, in particular benign versus malignant. Thus, correcting PET max-uptake-values has the potential to improve the classification of PET-positive pulmonary nodules.
Databáze: OpenAIRE