Electrochemical impedance spectroscopy in chromatography paper and its application to latex bead detection

Autor: Fumitaka Hori, Masashi Miki, Shohei Iwahara, Shigeyasu Uno
Rok vydání: 2014
Předmět:
Zdroj: Japanese Journal of Applied Physics. 53:04EL07
ISSN: 1347-4065
0021-4922
DOI: 10.7567/jjap.53.04el07
Popis: The principle of the quantitative immunochromatographic strip test (IST) is proposed. Electrochemical impedance spectroscopy is shown to be capable of detecting latex beads in chromatography paper, where latex beads can serve as a label in IST. Measurements to examine the impedance changes in the absence and presence of latex beads are conducted. In the presence of latex beads, an increase of 12.5% in the bulk solution resistance is observed. This indicates that the latex-bead-labeled antigen–antibody complex can be detected electrochemically by actual IST.
Databáze: OpenAIRE