Treatment with fibrinogen γ-chain peptide-coated, adenosine 5′-diphosphate-encapsulated liposomes as an infusible hemostatic agent against active liver bleeding in rabbits with acute thrombocytopenia

Autor: Shuhji Seki, Mami Doi, Keiichi Iwaya, Shinji Takeoka, Rempei Yanagawa, Manabu Kinoshita, Kahoko Nishikawa, Yasuhiro Nishida, Kohsuke Hagisawa, Hidenori Suzuki, Makoto Handa, Daizoh Saitoh
Rok vydání: 2014
Předmět:
Zdroj: Transfusion. 55:314-325
ISSN: 0041-1132
DOI: 10.1111/trf.12829
Popis: Background We evaluated the hemostatic efficacy of H12-(adenosine 5′-diphosphate [ADP])-liposomes in the setting of active liver bleeding in rabbits with dilutional thrombocytopenia after massive transfusion. Study Design and Methods Acute thrombocytopenia (platelet [PLT] count
Databáze: OpenAIRE