Association of TP53 codon 72 polymorphism with TP53 mutation in triple-negative breast cancer (TNBC) patients

Autor:	Matthias Preusser, Christoph C. Zielinski, Ansgar Weltermann, Elisabeth Bergen, Regina Promberger, Michael Gnant, Mathilde Födermayr, Miriam Sebesta, Rupert Bartsch, Margaretha Rudas, Anna S. Berghoff, Otto Zach, Peter Dubsky, Guenther G. Steger
Rok vydání:	2014
Předmět:	Genetics Cancer Research Protein function Oncology TP53 Codon 72 Polymorphism medicine Missense mutation Single amino acid Biology Carcinogenesis medicine.disease_cause Tp53 mutation Triple-negative breast cancer
Zdroj:	Journal of Clinical Oncology. 32:1130-1130
ISSN:	1527-7755 0732-183X
Popis:	1130 Background: A high rate of TP53 mutations was observed in TNBC, suggesting a role in TNBC carcinogenesis. Missense mutations cause single amino acid substitutions with altered protein function...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::0ebc9c475f3ef58ad5496691a4d401de https://doi.org/10.1200/jco.2014.32.15_suppl.1130 Zobrazit plný text záznamu