Neuropathy and levodopa in Parkinson's disease: Evidence from a multicenter study
| Autor: | Maurizio Melis, Valentina Nicoletti, Aristide Merola, Lucio Santoro, Paolo Contu, Daniela Frosini, Paolo Barone, Giovanni Cossu, Davide Manca, Roberta Marchese, Ubaldo Bonuccelli, Fiore Manganelli, Rosa Iodice, Giovanni Abbruzzese, Alessandra Mereu, Leonardo Lopiano, Marina Picillo, Maurizio Zibetti, Paolo Borelli, Alessandra Paribello, Monica Bandettini di Poggio, Roberto Ceravolo |
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| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Levodopa Parkinson's disease Homocysteine business.industry Odds ratio medicine.disease Gastroenterology Confidence interval Surgery chemistry.chemical_compound Peripheral neuropathy Neurology chemistry Internal medicine Medicine Neurology (clinical) Vitamin B12 Risk factor business medicine.drug |
| Zdroj: | Movement Disorders. 28:1391-1397 |
| ISSN: | 0885-3185 |
| DOI: | 10.1002/mds.25585 |
| Popis: | The objectives of this study were to evaluate the risk of neuropathy in patients with Parkinson's disease (PD) and to evaluate the role of levodopa exposure as a potential risk factor. A multicenter study of 330 patients with PD and 137 healthy controls with a comparable age distribution was performed. With respect to levodopa exposure, 144 patients had long exposure (≥ 3 years) to levodopa (LELD), 103 patients had short exposure ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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