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Background and Objectives: To evaluate the safety and efficacy of a home-use hair removal diode laser (TRIA Beauty, Inc., Dublin, CA) in a multiple treatment regimen. Study Design/Materials and Methods: Thirteen indicated adults with naturally brown or black hair and Fitzpatrick skin type I–IV received 8 monthly treatments with the diode laser at three fluences, with a fourth area left untreated as a control. Quantitative hair counts were made at each treatment visit and periodically for 12 months after the last treatment. Results: The treated sites exhibited statistically significant hair count reduction that generally increased with each treatment and remained stable during the 1 year follow-up period. The mean percent hair count reduction was 47%, 55%, and 73% at 1 month after the last treatment and 44%, 49%, and 65% at 12 months after the last treatment at fluences of 7, 12, and 20 J/cm 2 , respectively, compared to control. Eighty-six percent (86%) of subjects had greater than 30% hair reduction and 38% had >80% hair reduction at 12 months post-treatment. At the same time point, 31% of subjects reported complete (100%) hair removal and 69% reported that the hair that did regrow was less noticeable due to being finer and/or lighter. The only observed side effects were erythema and edema that were mild, transient, and self-resolving usually within a few hours. Conclusions: The home-use diode laser was safe and highly effective at permanently reducing unwanted hair. Lasers Surg. Med. 44:550–557, 2012. 2012 Wiley Periodicals, Inc. |